Biomedica Lactulose Syrup

Biomedica Lactulose Syrup
Biomedica Lactulose Syrup

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The drug contains lactulose. It is an osmotically acting laxative (laxative). Lactulose also exhibits a prebiotic effect. The drug is used:

  • in chronic constipation caused primarily by impaired defecation reflex due to bad habits or the need for soft stools.
  • on the advice of a doctor in portosystemic encephalopathy (central nervous system disorders that accompany liver damage).

Method of use

Dosage and dosage schedules

1 ml contains 0.667 g of lactulose.

For constipation and to facilitate defecation:
The dosage is adjusted according to the individual patient's response, usually starting with a higher dose, which is reduced after 3 days.

The initial dose is 15 - 45 ml (1 - 3 tablespoons) (equivalent to 10.005 g - 30.015 g of lactulose) per day.
For long-term administration, 10 - 25 ml (2 - 5 teaspoons) (equivalent to 6.67 g - 16.675 g of lactulose) per day.

Up to 1 year: 2.5 - 5 ml (half to 1 teaspoon) (equivalent to 1.6675 g - 3.335 g of lactulose) per day.
From 1 - 6 years: 5 - 10 ml (1 - 2 teaspoons) (equivalent to 3.335 g - 6.67 g of lactulose) per day.
Ages 7-15: Initial dose: 15 ml (1 tablespoon) (equivalent to 10.005 g of lactulose). Next: 5 - 10 ml (1 - 2 teaspoons) (equivalent to 3.335 g - 6.67 g of lactulose) per day.
With insufficient effect, the dose can be increased. After the therapeutic effect has been achieved, an appropriately reduced maintenance dose is administered.
Usually, a full daily dose is taken once a day after breakfast.

Portosystemic encephalopathy:
Dosage is individual.

Usually 30-90 ml (2-6 tablespoons) (equivalent to 20.01 g-60.03 g of lactulose) is taken daily, divided into 3 doses after main meals.
Treatment is started with lower doses and gradually increased to the optimal dose at which the patient has 2-3 soft stools daily, stool pH should be 5.0-5.5.
If diarrhoea develops, the dosage is reduced accordingly.

In children, the dosage is reduced by half.

Method of use

The vial should be shaken thoroughly before each use. The drug is taken after a meal and washed down with plenty of liquid (water, tea, fruit juices).


The drug can be used during pregnancy and breastfeeding.
It is given to children only on the advice of a doctor, there must be particularly compelling reasons for giving it to children under 1 year of age.
The drug contains lactose.
Store at temperatures up to 25°C.
Further special warnings are given in the SPC (section 4.4).

Active ingredients


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